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In a separate analysis in neuronal cells, overexpression of GPx-1 and other antioxidant enzymes also blocks AIF-translocation from mitochondria to the nucleus in a model of ischemia-induced apoptosis (404), suggesting that intracellular oxidants can promote AIF transmigration

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doi: 10.1038/s41420-023-01490-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 331.Li J, Wang Q, Xia G, et al